What is the importance of the correct choice of solvent to the chromotographic separation?

this is for paper chromatography..

The proper choice of solvent will ensure the best separation possible so the individual components will be separated with no co-elution taking place.
The solvent needs to dissolve the material completely. You also need solvent(s) with the necessary polarity (or dielectric constant) to separate the material you want from the impurities/side products.
Your choice of solvent depends on the polarity of your sample. The sample must be soluble in the solvent but not too much or the sample will just travel with the solvent front. For seperation of different components in the sample, they have to react differently to your solvent, thus traveling at different speeds. This is why most often a mixture of two solvents with very different polarity are used.

The answers post by the user, for information only, FunQA.com does not guarantee the right.

More Questions and Answers:
  • Information/ background on Ionic Bonds? Info/background on salts?
  • Mass of flask, boiling stone, foil cap, and unknown after cooling, g 83.350?
  • Lewis Dot Structure for NO2-, Electron Geometry and Bond Angle?
  • Why would popcorn salt burn my tongue?
  • Convert 1 metric tonne of palm oil to litters?
  • Chemistry help?
  • Chemical name & Formula?
  • Universal Solvent-Water?
  • Protease inhibitors, which one to use?